Gene variant effects across sodium channelopathies predict function and guide precision therapy

Welcome to another episode of The Brain Podcast (first for 2023!) - the official podcast for the journal Brain and sister journal Brain Communications. In this episode, three guests joined us to discuss the article entitled: Gene variant effects across sodium channelopathies predict function and guide precision therapy. Professor Andreas Brunklaus (first author) and Professor Stephanie Schorge (senior author) discuss their fascinating data-driven approach to better understand how mutations in sodium channels affect function with potential for precision therapy. We were fortunate to also e joined by Professor Massimo Mantegazza, who provided additional expert opinion.  Enjoy this rich, in-depth discussion!  Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac006 This episode was hosted, edited and produced by Xin You Tai; co-hosted by Professor Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Om Podcasten

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals. The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists