Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis

Welcome to the 10th episode of The Brain Podcast - the official podcast of the journals Brain and Brain Communications. In this episode we speak with Hideaki Nishihara and Britta Engelhardt, lead authors of the article entitled: Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis This was a transcontinental recording with our guests dialing in from Japan and Europe. The article explores blood-brain barrier dysfunction as a pathogenic process of multiple sclerosis. The authors discuss the use of a novel in vitro model of the blood-brain barrier which was designed to capture the activity of adhesion molecules involved in leukocyte trafficking.  Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac019 This episode was co-hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.

Om Podcasten

A fascinating, informative and digestible podcast highlighting the rich and diverse neuroscience published in the Brain journals. The episodes will take the format of interviews with article authors and the aim is to produce an informal and enjoyable podcast that appeals to a broad audience including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists