49ers in Five: Isaac Guerendo WILL play tonight vs. the Rams

49ers in Five: Isaac Guerendo WILL play tonight vs. the Rams San Francisco 49ers RB Isaac Guerendo will try and play on a foot sprain against the Los Angeles Rams, according to Adam Schefter. Plus, George Kittle predicts a breakout game for Deebo Samuel, and Brock Purdy scouts the Rams defense. One Thing to Read: https://www.espn.com/nfl/insider/story/_/id/42910575/2025-offseason-moves-fix-49ers-bengals-cowboys-jets-trades-cuts-firings-signings CHECK OUT AURA FRAMES! Save on the perfect gift by visiting AuraFrames.com to get $35-off Aura’s best-selling Carver Mat frames by using promo code [GOLD] at checkout. That’s A-U-R-A Frames.com promo code [GOLD]. This deal is exclusive to listeners, so get yours now in time for the holidays! Terms and conditions apply. CHECK OUT UNDERDOG FANTASY: Sign up and deposit for Underdog HERE with promo code GOLDSTANDARD to get up to $1,000 in bonus cash and a free pick: underdogfantasy.com or download the app. Must be 18+ (19+ AL, Nebraska; 19+ in CO for some games, 21+MA & AZ) and present in a state where Underdog Fantasy operates. Terms apply. Void in CO. Concerned with your play? Call 1-800-GAMBLER or visit www.ncpgambling.org; AZ: 1-800-NEXT-STEP (1-800-639-8783) or text NEXT-STEP to 53342; NY: Call the 24/7 HOPEline at 1-877-8-HOPENY or Text HOPENY (467369) JOIN OUR YOUTUBE CHANNEL TO GET ACCESS TO PERKS: https://www.youtube.com/channel/UCdn6zbhFQ7_vMLYfjSiLSYA/join GET SOME SWEET HOMAGE 49ERS GEAR HERE: https://homage.sjv.io/GoldStandard SUPPORT OUR PATREON: https://www.patreon.com/GoldStandard49ersPodcastNetwork CHECK OUT OUR WEBSITE: https://www.GoldStandardNiners.com SUBSCRIBE TO OUR YOUTUBE PAGE: https://www.youtube.com/@goldstandardnetwork FOLLOW US ON SOCIAL MEDIA: Instagram: https://www.instagram.com/gsn49ers/ Facebook: https://www.facebook.com/profile.php?id=100091816680160 Twitter: https://twitter.com/GSN49ers SUBSCRIBE TO OUR PODCASTS: Apple: https://podcasts.apple.com/us/podcast/the-gold-standard-san-francisco-49ers-podcast-network/id1524313515 Spotify: https://open.spotify.com/show/3mWHKNWMdC6Pojka3tyBio?si=ed9ef03ba95140e4 Learn more about your ad choices. Visit megaphone.fm/adchoices